From the discovery of tubulin to the approval of vinblastine for anticancer treatment, it has been more than half a century. Microtubules play an extremely important role in cell division, and disruption of the formation of mitotic spindles affects all dividing cells. For cancer cells that proliferate faster than… Continue Reading The development of microtubule inhibitors – the big story of small molecules

Metformin has been discovered for nearly 90 years. The advantages of safety, efficacy, and low price make it the most widely used oral hypoglycemic agent in clinical practice. In 2014, approximately 14.4 million people in the United States prescribed drugs containing metformin. As evidence of the benefits of metformin in… Continue Reading Hypoglycemic + antihypertensive = anticancer? The miracle metformin is up again