On March 4, Novartis published a clinical trial of a Phase III study of Cosentyx in the treatment of moderate to severe plaque psoriasis at the 2019 Annual Meeting of the American Academy of Dermatology (AAD2019). The reason for this study is that 441 of the 543 patients with… Continue Reading The third phase of clinical data of Cosynmyx China, a new psoriasis drug, was released for the first time: excellent efficacy and significant benefit

  A female patient, 53 years old, found “rheumatoid arthritis” for 14 years. She was treated with “painkiller” for a long time. She had chronic stomach and enteritis a few years ago and her diet has been bad. Recently, the body was extremely weak and struggling to walk. The family… Continue Reading Long-term use of painkillers, the consequences may be more serious than you think

  On February 27th, Bayer announced its 2018 financial report. The Group achieved a total revenue of 39.586 billion euros, an increase of 13.1% compared with 2017. The total revenue of the pharmaceutical business was 16.746 billion euros (-0.6%), the income from consumer health business was 5.45 billion euros (-7%),… Continue Reading Bayer 2018 earnings report: Acarbose reverse growth! New drug development is broken, the structure is about to be adjusted

  Drug: CAR-T therapy Magazine: Nature Highlights: A clever design that increases the anti-cancer ability of CAR-T therapy   More and more cancer patients are being treated with CAR-T cell therapy.   CAR, the English full name of Chimeric Antigen Receptor, chimeric antigen receptor, is a kind of “navigation” that… Continue Reading Upgraded version of CAR-T therapy, greatly improved anti-cancer ability

  Human immunodeficiency virus (HIV) is a retrovirus that infects cells of the human immune system, destroying or damaging its function. There is no symptom at the beginning of HIV infection, but as the infection progresses, the immune system begins to weaken. The final stage of infection is the acquired… Continue Reading Can immunotherapy create a miracle to cure AIDS?

  In November last year, the Financial Times discussed some of the characteristics of the transformation of the Chinese pharmaceutical industry at the “2018 Pharmaceutical & Biotechnology Summit” held in London. At the meeting, the host threw out a poll of “When do you think China might become an important… Continue Reading The new road of Chinese pharmaceutical companies

  Drug: maraviroc Magazine: Cell Highlights: 1) First confirmed that CCR5 gene is associated with stroke rehabilitation 2) HIV drug maraviroc can promote recovery of mice from stroke 3) First reported the function of CCR5 in the human brain   Stroke is an acute cerebrovascular disease caused by sudden rupture… Continue Reading Are HIV drugs used for “stroke rehabilitation”? Cell first confirmed that the genes edited by He Jiankui affect the human brain

  Azithromycin is a macrolide antibiotic commonly used in outpatient clinics. At present, a clinical use is popular. Azithromycin is orally administered for 3 days and stopped for 4 days. Is this usage correct?   I. When can azithromycin be used? Azithromycin against Gram-positive bacteria (Staphylococcus aureus, Group A hemolytic… Continue Reading Azithromycin, eat 3 days and stop for 4 days, is this usage correct?

  Cimetidine, also known as Methylene guanidine, is a H2 receptor blocker commonly used in primary clinical practice. It has preventive and protective effects against corrosive gastritis caused by chemical stimulation, and stress gastric ulcer and upper digestion. The bleeding also has obvious curative effect and is therefore widely used… Continue Reading 23 clinical new uses of cimetidine

  I. Sulfasalazine Mainly used for inflammatory bowel disease, rheumatoid polyarthritis, hemorrhagic proctitis. 1. Usage and dosage The initial dose is 1~2g per day, divided into 3~4 times orally; in the first few weeks, gradually increase the dose to 3~4g a day, orally 3~4 times; after the symptoms improve, it… Continue Reading The first dose of these drugs must be reduced