The onset of allergic rhinitis not only brings many troubles to the patient’s work and life, but also may cause serious adverse reactions to patients due to irrational use of drugs. The following authors talk about the differences between commonly used drugs for the treatment of allergic rhinitis according… Continue Reading The difference between commonly used drugs for allergic rhinitis

  Clinical outcomes are one of the gold standards for assessing the availability of new drugs, which often determines their reputation after listing. As a “living drug”, CAR-T therapy is to collect blood from patients, transport blood samples to the production GMP center, extract and purify T cells, lentivirus transfection… Continue Reading CAR-T production, outsourcing or building your own factory?

  Oral ulcer Oral ulcers, commonly known as “mouth sores”, are ulcerative lesions of the oral mucosa. The symptoms are more common in the inner side of the lips, the tongue, the abdomen, and the buccal mucosa. When the oral ulcers occur, the pain is strong, and the local burning… Continue Reading Drugs that can cause oral problems

  Not recommended Aspirin: acetylsalicylic acid Function characteristics: antipyretic and analgesic effect is strong and rapid, and also has anti-inflammatory, anti-rheumatic, anti-thrombosis effect. The main adverse reactions: the most common adverse reactions are gastrointestinal reactions, and even can cause gastric ulcer and stomach bleeding; damage to liver and kidney function;… Continue Reading About children’s antipyretics

  There is an uncle, 50 years old, slightly fat, hyperuricemia for more than 10 years, blood uric acid highest 620μmol / L, the lowest after diet control is 540μmol / L. He usually does not need medicine, and he uses a painkiller when there is a gout attack. A… Continue Reading Why are so many people unable to get rid of gout?

  Diarrhea is a group of digestive tract syndromes characterized by multiple pathogens and multiple factors, characterized by increased stool frequency and changes in stool characteristics. The incidence of infants and young children from 6 months to 2 years old is high, and half of them are within 1 year… Continue Reading 8 questions about autumn diarrhea

  T cells have always been at the center of tumor immunotherapy. In recent years, CAR-T therapy has shown its power to treat certain types of cancer, and the FDA has approved two CAR-T therapies for the treatment of lymphoma or leukemia. At the same time, there are currently hundreds… Continue Reading How will CAR-NK therapy affect the progress of cell therapy?

  The original research pricing strategy caused controversy A few years ago, a group of oncologists wrote an editorial on drug prices, with the breakthrough tyrosine kinase inhibitor Gleevec (imatinib mesylate) as an example of extreme pricing practices. This has sparked a major discussion about the price and value of… Continue Reading Reflection on Gleevec pricing

  For some B-cell-related blood cancers, the efficacy of CAR-T therapy is unquestionable. Last year, the FDA approved two CAR-T therapies, and many pharmaceutical companies began investing a lot of money and manpower in the field. However, the clinical application of CAR-T therapy still faces many obstacles, such as toxicity… Continue Reading New directions for CAR-T treatment: autoimmune disease and graft versus host disease

Busy week for BCMA. On Monday, the FDA granted Gilead/Kite a CATMA-recognized CAR-T therapy orphan drug. At the same time, at the myeloma 2018 meeting, Amgen also announced early clinical data on its TBMA-targeted BiTE drug AMG-420. Affected by the data, the shares of Bluebird Bio and Celgene fell on… Continue Reading CAR-T confronts double antibodies, and Amgen’s drugs targeting BCMA may be a huge threat to Bluebird