IDO Inhibitor Stops Recruiting Patients in Multiple Clinical Trials On May 2, Incyte announced that multiple late-stage clinical trials of epacadostat with MSD, Bristol-Myers Squibb, and Aslicon PD-1/PD-L1 drugs will stop the recruitment of patients. At the same time, Bristol-Myers Squibb also stopped several clinical trials with the PD-1 combination… Continue Reading A week of news
This aspirin tablet-sized implant made from biodegradable materials will likely activate the patient’s anti-tumor immune response, thereby producing an anti-tumor effect. Implantable tumor vaccine Immunotherapy, which can activate the patient’s own immune system and kill tumor cells, is probably the hottest area of research and development of new drugs today.… Continue Reading Frontiers: Can tumor immune implants become a new breakthrough in cancer vaccines?
Dengue fever is a mosquito-borne viral infection that resembles flu and can develop into a fatal complication, namely severe dengue fever. The incidence of dengue fever has risen rapidly, mainly in the tropical and subtropical regions. About half of the world’s population is at risk of dengue fever. In some… Continue Reading Observing the Difficult Development Course of Dengue Fever Vaccine from the Rise and Fall of Dengvaxia
Since RNAi (RNA interference) was first discovered 20 years ago, researchers from both academic institutions and pharmaceutical companies have been hoping to develop this technology into new therapies that can treat diseases, but so far there is no one. Related drugs are listed. Fortunately, however, Alnylam Pharmaceuticals, a pioneer… Continue Reading After 20 years of agitation of RNAi drugs, hope is in sight.
Metformin was introduced in 1957 and has been used clinically for more than 50 years. It is currently one of the most widely used oral hypoglycemic agents in the world. Metformin has good evidence of efficacy and safety of single-agent/combination therapy, as well as evidence of good health economics. Regardless… Continue Reading Is it effective to use metformin for weight loss?
I Mysterious disappearing tumor In the oncology department for a long time, there is always a chance to meet miracles. About ten years ago, Archie Tse also worked at the Sloan-Kettering Cancer Center. At that time, he took over a patient with advanced pancreatic cancer. The prognosis of most patients… Continue Reading STING Hunter: Can a new generation of therapy sweep the field of tumor immunity?
Helping clients improve the efficiency of clinical development will continue to be the core competencies of clinical CRO companies in 2018 and in the future. Pharmaceutical companies will unremittingly find new ways to shorten the development cycle and reduce costs. Therefore, CRO companies that rely on professional skills rather than… Continue Reading Clinical CRO Industry Trends in 2018
Complex organic molecules are the basic components of life. We know from many astronomical observations that they are not exclusively owned by the Earth. There are lots of natural formations of organic biomolecules in the interstellar medium near the stars, comets, and even many planetary satellites in the solar system.… Continue Reading How is the basic composition of life formed in outer space?
The in vivo distribution of drugs is an important basis for the selection of antimicrobial drugs. Such as bacterial meningitis, it is appropriate to use a higher concentration of antibiotics in cerebrospinal fluid; Hepatobiliary system infection should choose the higher concentration of bile, and should be combined with possible pathogenic… Continue Reading Distribution of Antibacterial Drugs in Tissues and Organs
In 2017, it was honored as the first year of major changes in the intellectual property of pharmaceuticals. Patent linking system, orange book, patent term compensation, data protection system, these ever-familiar words are familiar to Chinese medicine people from this year. Both the generic medicine and the new medicine industry… Continue Reading An article to read the big game of drug patent link reform in China