According to AbbVie’s previous patent litigation settlement agreement with Amgen and Samsung Bioepis, Humira’s biological analogues officially landed on the European market on October 16, 2018. In addition, European listing applications for Humira analogues, including Boehringer Ingelheim, Mylan, etc., are also in the EMA approval process. In response to… Continue Reading Humira bio analogs officially launched, AbbVie Europe cuts prices by 80%

  Bloomberg reported that Jay Bradner, head of Novartis R&D, revealed that after conducting a comprehensive pipeline asset assessment, Novartis has reduced its number of new drug projects from 430 to 340. Jay Bradner Bradner said: “We have a good understanding of the scientific foundation behind these 90 projects. Although… Continue Reading Novartis R&D begins to slim down, 90 new drug projects will be shelved or transferred

  Sulfasalazine, mesalazine, olsalazine, and balsalazide are the main drugs for the treatment of inflammatory bowel disease (IBD), but the four drugs are very different. Only by mastering the differences between them can the drug be selected correctly.   I. Ulcerative colitis, the difference between Crohn’s disease If you don’t… Continue Reading The difference between sulfasalazine, mesalazine, olsalazine…

  The FDA issued a warning message on August 29, 2018: Cases of rare, severe genital and genital area infections of sodium-glucose cotransporter 2 (SGLT2) inhibitors have been received. This rare and serious infection is called perineal necrotizing fasciitis, also known as Funeral gangrene. The FDA believes that new warnings… Continue Reading Warning: This type of hypoglycemic agent can cause serious reproductive area infection

  1. Eat one or two uric acid-lowering drugs? The currently used uric acid-lowering drugs fall into two categories: reducing uric acid production and promoting uric acid excretion. The former includes allopurinol and febuxostat, the latter including benzbromarone. Special note: ibuprofen, futaline and other antipyretic analgesics, colchicine, hormones, etc. are… Continue Reading Eat one or two uric acid-lowering drugs?

  With the changes in living environment, allergic rhinitis (also known as allergic rhinitis) has become a common and frequently-occurring disease in children.   I. Simple identification of allergic rhinitis and common cold 1. The cause is different: the common cold is an infectious disease caused by a virus (in… Continue Reading How should children with allergic rhinitis be treated?

  Cellular therapies based on effector T cells over the past decade, particularly CAR-T therapy, have revolutionized the treatment of many types of cancer. In 2017, the FDA approved two CAR-T therapies for the treatment of certain types of cancer associated with B cells, and research in the field of… Continue Reading How to apply CAR-T therapy to treat autoimmune diseases?

  Drug Alerts: On July 12, 2018, the Australian Therapeutic Products Authority announced plans to adopt new risk management measures for the “famous” leukotriene receptor antagonist montelukast. – There is a known association between montelukast and neuropsychiatric events (such as excitement, sleep disorders, and depression), including suicidal ideation and behavior… Continue Reading Montelukast is associated with neuropsychiatric events, including suicide

  Since August 2017, the FDA has approved a total of four therapeutic drugs that are different from traditional small molecule drugs and macromolecular drugs. They are Novartis CAR-T drugs Kymriah (tisagenlecleucel-T) and Gilead (Kite). CAR-T drug Yescarta (axicabtagene ciloleucel), Spark gene therapy drug Luxturna (voretigene neparvovec-rzyl) and small interfering… Continue Reading The layout of global TOP10 pharmaceutical companies in the CAR-T field

  A woman developed cough symptoms after a cold, and she took amoxicillin and compound licorice mixture for 3 days, but it had no effect. Going to the hospital for chest X-ray examination was normal. The doctor thought she was suffering from a cough after a cold. She was treated… Continue Reading Cough after a cold, what medicine should I use?