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Many of the drugs we often have different treatment effects and adverse reactions due to different taking times. For example, the general blood pressure lowering drug should be taken on an empty stomach in the morning, but terazosin which is used to treat benign prostatic hyperplasia should be taken before bedtime.

Today, let’s take a look at the correct taking time of the common drugs in those pharmacies.


I. Antiasthmatic drugs

Antiasthmatic drugs should be taken at bedtime. Represents drugs such as salbutamol and bambuterol. But aminophylline should be taken around 7 am.


II. Antibiotics

1. General antibiotics are taken before meals, such as cefaclor and norfloxacin.

2. Take clarithromycin after a meal.

3. Azithromycin should be taken at least 1 hour before eating or 2 hours after eating.


III. Digestive system drugs

1. Promoting gastric motility drugs. Taken 30 minutes before meals, on behalf of drugs: domperidone, metoclopramide, mosapride, cisapride.

2. Suppress gastric acid drugs. Proton pump inhibitors (PPI) should be taken on an empty stomach in the morning or before going to bed, representing drugs such as omeprazole, pantoprazole, rabeprazole, and iprazol; the traditional regimen for H2 receptor blockers is Two times a day, before or after meals, you can also take a daily dose before going to bed every day to suppress nighttime acid breakthrough, representing the drug ranitidine and famotidine.

3. Gastric mucosal protection drugs.

① Tincture, which is potassium citrate 4 times a day, 0.3g each time, the first 3 times in the first half of the three meals before meals, the fourth time before going to bed with warm water delivery; colloidal pectin 铋 4 times a day, Take 1 hour before 3 meals and sleep. The stomach sputum magnesium tablets are washed with warm water after meals.

② Aluminum magnesium agent, taken 1-2 hours after meal and before going to bed, on behalf of drugs, aluminum magnesium carbonate, aluminum-magnesium plus suspension.

③ Aluminum agent, compound aluminum hydroxide tablets, half an hour before a meal or chew after gastric pain episodes; aluminum phosphate gel, esophageal disease is administered after meals. Esophageal hiatus, gastric-esophageal reflux, esophagitis are taken after meals and before going to bed at night. Gastritis and stomach ulcers are taken half an hour before meals. Duodenal ulcers are taken 3 hours after meals and when they are in pain; one hour before the sucralfate meal and before bedtime.

4. Cathartic, lactulose, take once at breakfast; open the plug, use in the morning; irritating laxative, take before bed, such as phenolphthalein tablets, bisacodyl.

5. Antidiarrheal drugs, such as montmorillonite powder, taken before meals.

6. Anthelmintic drugs, should be taken in the morning to reduce the body’s absorption of drugs. Represents the drug albendazole and piperazine phosphate.


IV. Non-steroidal anti-inflammatory drugs

Non-steroidal body can inhibit the synthesis of prostaglandins in gastric mucosa. It should be taken after meals, and it is representative of drugs such as aspirin, indomethacin and diclofenac sodium.


V. Glucocorticoid

Recommended glucocorticoids are administered at a daily dose between 7 am and 8 am to reduce and prevent adverse effects of adrenal insufficiency and cortical atrophy, and the incidence of digestive ulcer bleeding can also be reduced. Representative drugs such as prednisone, methylprednisolone and so on.


VI. Diuretics

Diuretics should be taken in the morning to avoid excessive urination at night. Represents the drug hydrochlorothiazide, furosemide.


VII. Antihypertensive drugs

1. The general antihypertensive drugs, taken once a day, should be taken from 7 to 8 o’clock to effectively control the blood pressure. Represents the drugs amlodipine, lacidipine, perindopril, losartan potassium, sotalol and the like.

2. With the treatment of benign prostatic hyperplasia terazosin should be taken before bedtime, so as not to cause orthostatic hypotension.


VIII. Lipid-lowering drugs

1. Statin lipid-lowering drugs, should be taken before bed to inhibit the synthesis of nighttime cholesterol, such as simvastatin, fluvastatin. However, atorvastatin and rosuvastatin have a longer half-life and can be taken at any time of the day.

2. Fibrate drugs, with meals, if combined with statins, should be taken in the morning.


IX. Hypoglycemic drugs

1. Sulfonylureas. Take 30 minutes before a meal to promote insulin secretion and exert maximum hypoglycemic effect, representing the drug glimepiride and gliclazide.

2. Metformin. Metformin sustained-release tablets are taken once a day at dinner; metformin enteric tablets are taken 30 minutes before meals to reduce gastrointestinal reactions; metformin tablets are taken immediately after meals or after meals.

3. Glinide class. Taken within 15 minutes before the meal, representing the drug repaglinide, nateglinide.

4. Insulin sensitizer. Take it once an hour on an empty stomach every morning, representing the drug pioglitazone.

5. α-glucosidase inhibitors. Take the first bite or take it immediately before the meal, which means the drug acarbose and voglibose.


X. Vitamins

1. Fat-soluble vitamins A, D, E, and K should be taken after eating and eating fat to help absorb.

2, vitamin C, B1, B2, take it after meals.


XI. Minerals

1. Calcium, should be taken before bed or early morning, such as calcium carbonate D3 tablets.

2. Iron, take after meals to reduce gastrointestinal irritation, such as ferrous succinate.


XII. Antiallergic drugs

Anti-allergic drugs should be taken 30 minutes before bedtime, representing drugs such as chlorpheniramine, cetirizine and so on.

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