The healthy growth of the baby is the wish of the father and mother. The physical development of the baby is very important, parents should pay special attention. Recently, some drugs have been gradually discovered during use, which can lead to growth and development disorders in infants and young children, causing great harm to children. Now we are uncovering the face of drug killers that affect the growth and development of infants and young children.
Adrenal cortex hormones (such as methylprednisolone, dexamethasone, etc.)
We all know that infants and young children rarely use hormonal drugs. Why do adrenal cortical hormones affect the growth and development of infants and young children?
The effect of this drug on infants and young children is mainly through milk. If breast-feeding women are treated with adrenocortical hormone for a long time, hormones can be excreted from the milk. Inhalation of infants and young children can inhibit the secretion of growth hormone from the pituitary gland, inhibit the function of the adrenal cortex, and reduce the sensitivity of peripheral tissues to hormones, eventually leading to growth retardation.
Long-term use of adrenocortical hormone in children or adolescents, prone to osteoporosis, femoral head necrosis, glaucoma, etc., should cause high attention.
Quinolone antibiotics (such as ciprofloxacin, ofloxacin, etc.)
Similar to adrenocortical hormone, most of these drugs can enter the placenta and milk. The concentration in the milk is close to the blood concentration, which has adverse reactions to infants and young children, so lactating women are prohibited.
In addition, quinolone antibacterial drugs can damage the weight-bearing cartilage joints, joint swelling, pain, and affect the growth of bones in the limbs.
The instructions for such drugs stipulate that the safety and effectiveness of the application in adolescents, pregnant women and lactating women under the age of 18 are not established and should be banned.
Because tetracycline has a high affinity for calcium, it can be incorporated into long bones very quickly. Drugs can be deposited in the growing bones and teeth of the fetus, newborn and children, causing discoloration of the teeth, poor enamel regeneration, and inhibition of bone growth in infants.
If the dose of tetracycline reaches 7 to 25 mg/kg body weight each time, 40% of children can be inhibited from growth and development.
Tigecycline is contraindicated in patients under 18 years of age, and minocycline is contraindicated in children under 8 years of age. Rat studies have shown that both tetracyclines can cause bone discoloration. Therefore, during tooth development, it should not be used unless other drugs are ineffective or contraindicated.
Central nervous system stimulants (such as dextroamphetamine sulfate, modidine, etc.)
For the treatment of children with ADHD, methylphenidate, dextroamphetamine sulfate, pimoline, modidine and other drugs are often used.
In a study of moroxime treatment for children with ADHD for 1 year, the height and weight indicators of children were lower than expected, and the extent was related to the dose and time of medication.
Long-term use of dextroamphetamine sulfate can inhibit the growth and development of children. When methylphenidate is used, it can cause loss of appetite, abdominal discomfort, and weight loss. Therefore, in the course of treatment with these drugs, it is necessary to monitor the growth and development of the children.