Aspirin: acetylsalicylic acid
Function characteristics: antipyretic and analgesic effect is strong and rapid, and also has anti-inflammatory, anti-rheumatic, anti-thrombosis effect.
The main adverse reactions: the most common adverse reactions are gastrointestinal reactions, and even can cause gastric ulcer and stomach bleeding; damage to liver and kidney function; excessive toxicity and specific salicylic acid allergic reaction is serious Or fatal adverse reactions; children with influenza (flu) or chickenpox after the drug may cause Reye’s syndrome, mainly characterized by acute encephalopathy and hepatic steatosis.
Note: The World Health Organization claims that aspirin should not be used in children with fever caused by acute respiratory infections. Its use is limited to children with rheumatic fever, juvenile arthritis and Kawasaki disease. The recommended atypical pneumonia (SARS) treatment plan in China stipulates: fever children Disabling aspirin.
Compound ammonia barbital: Antondine
Function characteristics: Among them, aminopyrine and antipyrine are pyrazolone antipyretic analgesics. As an injection, it is a potent antipyretic drug commonly used in clinical practice, with good antipyretic effect and poor safety.
The main adverse reactions: Aminopyrine can cause leukopenia in peripheral blood. If you inject this product repeatedly in a short period of time, it is easy to cause acute granular leukocyte deficiency. For some children, this drug can induce acute hemolysis. Anemia, rash and other adverse reactions; in addition to anaphylactic shock and exfoliative dermatitis.
Note: It is not suitable for continuous use; if the dosage of this product is too large, the child will sweat too much, and the body temperature will drop suddenly, which may cause collapse. Therefore, pediatric experts pointed out that infants and young children are banned from compound aminopyrine, and older children should be used with caution.
Function characteristics: Glucocorticoid drugs, due to rapid antipyretic effect and long duration, the aqueous solution preparation can solve the problem of difficulty in administration by intravenous administration, so individual physicians use it as an antipyretic drug.
The main adverse reactions: hormones may cause metabolic disorders in the body’s protein, fat and electrolytes, and more serious will cause muscle atrophy, affecting the growth and development of children.
Explanation: Hormone fever is only an illusion. It also masks the disease while it is feverish. Due to the inflammatory inhibition, the body’s resistance is reduced, which causes the infection in the body to expand and spread, which will aggravate the condition. Especially for bacterial infections, the use of hormones, such as the decline in body temperature and other illusions, often delay diagnosis and treatment.
The Guiding Principles for Clinical Application of Glucocorticoids states that it is forbidden to use glucocorticoids solely for the purpose of antipyretic and analgesic, especially for the purpose of antipyretic and analgesic in infectious diseases.
Antipyretic drugs are symptomatic treatments, and sometimes the symptoms may be affected by the use of drugs to cover the diagnosis. Therefore, children with unclear diagnosis should be used with caution;
Try to choose a dosage form that is easy for children to accept. It is not recommended for children to use an injection;
The antipyretic analgesics currently considered to be most suitable for children are acetaminophen and ibuprofen;
Paracetamol combined with ibuprofen is not recommended for use in children with fever, nor is it recommended for acetaminophen and ibuprofen to be used in children for fever;
Calculate the dose according to the age and weight of the child, avoid overdosing or over-frequency;
Children should avoid long-term use of antipyretic and analgesic drugs, the course of treatment should not be > 1 week.