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In order to treat a disease, doctors prescribe one or several drugs for symptomatic treatment, but sometimes these drugs may induce other diseases. In particular, the elderly have more diseases and more risks, especially the risk. For the safety of medication for the elderly, Europe, the United States and China have the criteria for unsuitable drug use under the disease state. Europe and the United States are for people over 65 years old. The judgment standard in China is over 60 years old. By combining the standards of three countries and regions, the elderly drug can be classified into the following six “avoidances”.

1. If the elderly have been diagnosed with heart failure, the following medications should be avoided:

Non-steroidal anti-inflammatory drugs (ibuprofen, loxoprofen, diclofenac, celecoxib, meloxicam, nimesulide, etc.), calcium antagonists (diltiazem, verapamil), hypoglycemic agents (pioglitazone, rosiglitazone), antiplatelet aggregation drug (cilostazol).

These drugs may increase fluid retention in the elderly and increase the risk of heart failure.

2. If the elderly have been diagnosed with dementia or impaired cognitive function, the following medications should be avoided:

Sedative hypnotics (eszolam, lorazepam, diazepam, alprazolam, clonazepam, nitrazepam, dextrozopicl, zolpidem, zaleplon), anticholinergic drugs ( Benzene, tolterodine, chlorpheniramine, diphenhydramine, antipsychotics (olanzapine, quetiapine, risperidone, aripiprazole, etc.).

These drugs can cause cognitive dysfunction in the elderly, especially antipsychotics can increase the risk of cerebrovascular accidents (stroke) and death in patients with dementia.

3. If the elderly have been diagnosed with Parkinson’s disease, all antipsychotics other than aripiprazole, clozapine, and antiemetics (metoclopramide, promethazine) should be avoided. These drugs can aggravate the symptoms of Parkinson’s disease in the elderly.

4. If the elderly have a history of gastric ulcer or duodenal ulcer, non-steroidal anti-inflammatory drugs, glucocorticoids (prednisone, dexamethasone, betamethasone, etc.) should be avoided. These drugs may aggravate existing ulcers in the elderly or cause new ulcers.

5. If the elderly suffer from chronic constipation, antipsychotics (haloperidol, fluphenazine), tricyclic antidepressants (dosepin, amitriptyline), anticholinergic drugs (toltero) should be avoided. Ding, chlorpheniramine, diphenhydramine, trihexyphenidyl, etc.). These drugs can aggravate constipation.

6. If the elderly have been diagnosed with gout, thiazide diuretic antihypertensive drugs (hydrochlorothiazide, furosemide, indapamide) should be avoided. These drugs can increase the blood uric acid in the elderly and cause gout.

Finally, remind elderly patients to explain the history of the disease and the history of medication to the doctor for the doctor to fully understand the condition and consider the medication. Once the original disease is aggravated after taking the medicine, immediately explain the situation to the doctor to facilitate timely adjustment of the medication plan.

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