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What is the “Smurf”?

“Smurf” is a prescription drug, which is actually “flunitrazepam”, a benzodiazepine sedative and hypnotic drug, which is similar in nature to diazepam (Natal).

Flunitrazepam is tasteless and odorless.

In order to increase the identifiability of flunitrazepam, some pharmaceutical companies have added a blue dye to flunitrazepam tablets, hence the name “Smurf”.

The half-life of flunitrazepam is about 16 to 35 hours, which is transmitted through the placental barrier and can be distributed in the milk.

Flunitrazepam can be used for short-term treatment of insomnia, for preoperative use, and for induction of anesthesia. The usual dose for the treatment of insomnia is oral 0.5~1mg, taken before bedtime.

For elderly patients or frail patients, the initial dose should not exceed 0.5 mg.

 

Medication

Precautions to patients and caregivers before medication:

Prevent falls!

Avoid driving!

Amnesia!

 

The damage is 1000 times that of the first generation of drugs.

Flunitrazepam has moderate abuse potential and may be higher than other benzodiazepines. Misuse can result in loss of behavior, after sexual assault, amnesia can occur, and can lead to drug-driven rape.

“I heard that after taking this one, you may not know a slap in the face. Most things will be forgotten when you wake up the next day. For girls, drinking this medicine is no different from walking naked. You will have no secrets in the eyes of others.”

As a prescription drug, the “Smurf” is soluble in water, and the liquid is light blue, but similar synthetic substances, some are colorless and odorless, and are not easily found after being dissolved in water.

The “Smurf” belongs to the new psychoactive substance. New psychoactive substances are also known as “third generation drugs.” It is worth noting that the third generation of drugs is extremely harmful to human health.

A small amount of new psychoactive substances, people will have acute symptoms such as accelerated heartbeat, elevated blood pressure, liver and kidney failure. A large number of people will cause paranoia, anxiety, panic, paranoia and other reactions, severe mental confusion, and even convulsions, shock, stroke and death, the damage is 1000 times the first generation of drugs.

The new psychoactive substances are mainly based on central excitatory and hallucinogenic effects. In the case of acute poisoning after abuse, the main manifestations are uncontrollable excitement, irritability, impulsivity, and sexual disorder, which leads to sexually transmitted diseases, AIDS, and hepatitis. The spread of infections such as infectious diseases.

 

Benzodiazepine adverse reactions

1. More common adverse reactions

Excessive sedation is the most common adverse reaction, often the continuation of the nighttime hypnotic effect of the drug during the day, such as hangover effect, drowsiness, lethargy, fatigue and so on. It is usually the most significant within two hours after taking the drug, and drugs with a long half-life are prone to occur.

In high-dose or long-term use, due to the enhancement of cerebellar GABA neurons, exercise and disturbance of consciousness can occur, manifested as tremor, ataxia and disorientation. In severe cases, coma can occur, especially in elderly and frailty, liver and kidney dysfunction and when combined with other sedatives.

2. Less adverse reactions

Some users may experience impaired cognitive function, which is characterized by slow response, decreased alertness and attention, and memory loss. Short-term use may interfere with the formation and consolidation of memory, leading to antegrade forgetting.

Although it can prolong the total sleep time, it will damage and reduce slow wave sleep and fast eye movement sleep.

Muscle relaxation can occur after use, causing users to fall and get hurt, especially for elderly users. These accidents occur mostly within the first 2 weeks of taking the drug, and the dose increase is too fast and the dose is too large is the main risk factor. Muscle relaxation is more common with clonazepam.

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