Herpes zoster is an acute infectious skin disease caused by the recurrent varicella-zoster virus in the body. The main symptom of this disease is clustered vesicles, which are clustered along the peripheral nerves of one side, accompanied by obvious neuralgia.
How do you get herpes zoster?
When the body’s immunity declines or is stimulated by physical and chemical factors, the varicella-zoster virus that is lurking in the ganglion is activated, causing inflammation or necrosis of the affected ganglia and causing neuralgia. At the same time, the reactivated virus can proliferate along the axons to the inner skin cells, and a band of herpes is present in the skin area innervated by the ganglia.
How is herpes zoster treated?
General treatment principles: rest, protect skin lesions, avoid friction and external stimuli, actively look for predisposing factors, give appropriate treatment and treatment, avoid contact with children with low resistance and pregnant women.
Principles of systemic therapy: antiviral, analgesic, anti-inflammatory, shortening the course of the disease, protecting the skin and preventing secondary infections.
What are the drugs for treating herpes zoster?
When the patient is diagnosed with herpes zoster, medication should be applied reasonably under the guidance of a doctor to relieve symptoms, relieve the condition, and reduce complications. Next, follow the arrangement of Yi Xian Pharmacist to find out what medicines to treat herpes zoster.
1. Therapeutic drugs: antiviral drugs
Herpes zoster is induced by the activation of DNA viruses that are latent in the body. In the case of indications of useful drugs, systemic antiviral therapy should be performed as soon as possible, and the best period of treatment within 48-72 hours after rash. Commonly used antiviral drugs are nucleoside antiviral drugs. Nucleoside anti-DNA virus drugs can inhibit DNA replication and have a role in both herpes virus and poxvirus.
2. Symptomatic treatments: analgesics and sedatives
Since herpes zoster is an acute inflammation of the peripheral nerve root caused by the virus, neuralgia is one of the main clinical symptoms. Pain can occur before or after a rash, and the older the person, the more severe the pain.
In response to this symptom, analgesics should be given to relieve pain and reduce damage to the nerves. For postherpetic neuralgia (PHN, stubborn neuralgia left after the rash subsided, it is one of the main sequelae of herpes zoster, the etiology and pathogenesis are unknown), and analgesics and sedatives are needed.
3. Nutritional nerve drugs
Such as vitamin B1, vitamin B6, mecobalamin and the like. For example, mecobalamin is a neurotrophic drug endogenous coenzyme B12, involved in the synthesis of thymidine in brain cells and spinal cord neurons, promoting the utilization and metabolism of folic acid, promoting lecithin synthesis and neuronal myelination, accelerating The contact is restored to achieve analgesia and promote the recovery of damaged nerves.
Hormones: Reasonable oral corticosteroids such as prednisone in the early stage of acute herpes zoster can inhibit the inflammatory process and shorten the course of the disease. It is not recommended to use it alone without systemic antiviral therapy. Patients with low immunity should not be used.
Immunomodulators: Because herpes zoster occurs when the body’s immunity is low, drugs that enhance immune function such as thymosin, pidotimod, and spleen amino peptide lyophilized powder can be used as appropriate to reduce symptoms and shorten the course of disease.
4. External use
Topical therapy, mainly dry and anti-inflammatory, such as acyclovir ointment when the herpes is not broken; or calamine lotion. If the herpes has collapsed, it may be applied with a 3% boric acid solution or a neomycin ointment.
In summary, clinically, the indications for the useful indications for herpes zoster should be systematically used as antiviral drugs as soon as possible. For neuropathic pain, rational analgesic sedatives should be selected according to the stepwise therapy, and hormone drugs can be added reasonably according to the patient’s condition. , nutritional neuropharmaceuticals, immunomodulators, etc., can be supplemented with other drugs, if the patient’s blister ulceration causes infection, if necessary, antibiotic treatment.