Montmorillonite is an intestinal mucosal protective agent and adsorbent. It has the function of adsorbing intestinal toxins and protecting intestinal mucosa. It can be used clinically to treat acute or chronic diarrhea, or to assist in the treatment of esophageal, gastric and duodenal diseases.
So, what are the pharmacological characteristics of this drug? How to take it correctly? How to use with other medicines?
Montmorillonite powder, the main component is octahedral smectite particles, which is an aluminosilicate. Its pharmacological characteristics are as follows:
1. Adsorption characteristics
The drug can adsorb Escherichia coli, Vibrio cholerae, Campylobacter jejuni, Staphylococcus aureus, rotavirus and bile salts.
2. Fixed characteristics
Montmorillonite powder can strongly immobilize and inhibit the viruses, bacteria and toxins produced in the digestive tract.
3. Gastrointestinal mucosal protection and repair characteristics
The drug has the ability to cover the mucosa of the digestive tract and can be combined with mucus glycoprotein, thereby increasing the amount of mucus, improving the quality of mucus and improving the cohesion and elasticity of mucus, thereby improving the defense ability of the intestinal mucosal barrier against attack factors, and finally exerting digestion. The protection and repair of the mucosa.
4. Pain relief characteristics
Montmorillonite has a local analgesic effect.
In addition, the drug does not enter the blood circulation after oral administration and is excreted together with a fixed attack factor. It does not change the color of the stool and does not change the normal bowel movements. But do not take too much, otherwise it may cause constipation.
I. Principles of usage and dosage
① Usage: Montmorillonite will adhere to food and reduce its ability to attach, so it is recommended to take it before meals.
② Special dosage: used in acute diarrhea, can reduce the number of diarrhea and diarrhea time, but the first dose needs to be doubled. 1 bag or 3g can be poured into 50ml of warm water, stir well and then take, but note that the drug concentration should not be too high or uneven, so as not to affect the efficacy.
II. Principles for use with other medicines
① Combined with antibacterial drugs: it is recommended to use antibacterial drugs first, then take montmorillonite powder, the two drugs at least 1 hour apart.
Reason: On the one hand, montmorillonite can adsorb bacteria, viruses and bile salts, and on the other hand, it can strongly immobilize and inhibit the viruses, bacteria and toxins produced in the digestive tract. Therefore, after killing pathogenic microorganisms with antibacterial agents, montmorillonite is used to disperse bacteria or various toxins, especially pathogenic Gram-negative endotoxin.
② In combination with microecological preparations (probiotic preparations): It is recommended to use montmorillonite powder first, then use microecological preparations (probiotic preparations), and the two medicines should be separated by at least one hour.
Reason: montmorillonite powder can adsorb bacteria or viruses in the gastrointestinal tract, and at the same time protect and repair the digestive tract mucosa. Then take probiotics to restore normal intestinal flora and improve the disorder of the flora.
If the above three drugs are combined, the antibacterial agent may be taken first, then the montmorillonite powder is used, and finally the probiotic preparation is used, and the 3 drugs are separated by at least one hour.
In addition, because the drug has a certain physical adsorption, it is recommended to take another period of time, such as 1-2 hours.
III. Principles for the use of special populations
① Pregnant woman: The drug does not enter the blood circulation after taking the drug, and will be excreted with the fixed attack factor along with the gastrointestinal tract itself, without affecting the normal intestinal peristalsis. Therefore, pregnant women can take it safely.
② X line checker: montmorillonite powder does not affect X-ray examination.
③ Oral ulcers: montmorillonite powder can repair the oral mucosa, the drug is adjusted into a paste, after the meal with a cotton swab on the ulcer.