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Aspirin

If there is a magic drug in the world, it must be aspirin.

Aspirin, also known as acetylsalicylic acid, is a long-standing antipyretic analgesic that was born on March 6, 1899. It is different from the current western medicine. It doesn’t have five or six hundred molecular weights, and it has no fancy structure. He only evolved from the bark of the poplar, gaining fame, but low-key to the dust.

It is not only used for the treatment of colds, fever, headaches, toothache, joint pain, rheumatism, but also has the inhibitory effect on platelet aggregation can be described as “a special versatile”, so many people called it “universal magic drug.” However, the role of aspirin is far more than these.

Promote the role of anti-cancer agents:

Recently, according to the biological exploration report, a new study published by Clinical Cancer Research at the University of Queensland, Australia, showed that the addition of aspirin to some existing anti-cancer drugs can increase the effectiveness of anti-tumor therapy.

The author of the article, Helmut Schaider, said: “We have found that adding aspirin to the cancer inhibitor Sorafenib can enhance its effectiveness in mouse models of lung cancer and melanoma that have mutations in the RAS gene.”

At the same time, the researchers believe that adding aspirin may also prevent the recurrence of tumors in patients. A joint study of aspirin and other anti-cancer drugs is already in progress.

Anti-cancer effects:

According to a Russian satellite network report, scientists said at the meeting of gastroenterologists in Barcelona, ​​Spain, that taking small doses of aspirin can repeatedly reduce the risk of cancer in the liver, stomach, and most of the organs related to digestion and metabolism. .

According to doctors who do experiments, aspirin can increase the efficiency of immunotherapy several times, and it can also independently combat leukemia, rectal cancer and other tumors, and can increase the chance of survival after chemotherapy by 15-20%.

Helps repair cavities:

Recently, researchers from Queen’s University in the United Kingdom have found through research that aspirin can effectively reverse the effects of tooth decay, which may reduce the need for dental filling.

Studies have found that low-dose aspirin can significantly increase the mineralization of teeth and enhance the expression of genes that form dentin, which can often damage the structure of hard teeth in teeth. The researchers pointed out that aspirin has anti-inflammatory properties and slows pain. The effect may be entitled a solution to help control the neuralgia and inflammation caused by an individual’s tooth decay while also promoting natural tooth restoration.

Metformin

Mention metformin can be traced back to the 1920s. It is an anthraquinone substance extracted from a plant called “goat bean”. In 1957, metformin was officially applied in clinical practice. Since then, together with aspirin, he has laid down the banner of “magic drug.”

Metformin is a type of “authoritative” medication for the treatment of type 2 diabetes, and is listed as a first-line hypoglycemic agent in various treatment guidelines at home and abroad. The drug has the advantages of definite hypoglycemic effect, low risk of hypoglycemia, low price, etc. It is currently one of the most widely used Class A hypoglycemic drugs.

In recent years, with the deepening of research, metformin has many surprising findings beyond the hypoglycemic effect.

Anti-aging effects:

At present, the U.S. Food and Drug Administration has approved clinical trials for the use of metformin against aging. The reason why foreign scientists used metformin as an anti-aging drug candidate may be because metformin can increase the number of oxygen molecules released into cells. At first, this seems to increase the body’s strength and prolong life.

Weight loss effect:

Metformin is a hypoglycemic drug that can lose weight. It can increase insulin sensitivity and reduce fat synthesis. For many type 2 sugary friends, the weight loss itself is a good thing for blood sugar stability control.

A study by the American Diabetes Prevention Program (DPP) research group showed that in the unblinded study period of 7 years to 8 years, patients treated with metformin lost an average of 3.1 kilograms.

Cardiovascular protection:

Metformin has a cardiovascular protective effect and is currently the only hypoglycemic agent recommended by the diabetes guidelines as evidence of a clear cardiovascular benefit. Studies have shown that long-term treatment with metformin is significantly associated with a reduced risk of cardiovascular disease in patients with newly diagnosed type 2 diabetes and type 2 diabetes who already have cardiovascular disease.

Improve polycystic ovary syndrome:

Polycystic ovary syndrome is a heterogeneous disease characterized by hyperandrogenism, ovarian dysfunction, and polycystic ovary morphology. Its pathogenesis is unclear and patients often have hyperinsulinemia at different levels. Studies have shown that metformin can reduce hyperinsulinemia by reducing insulin resistance and restoring ovulatory function.

Anti-cancer, anti-tumor effects:

In recent years, a number of epidemiological data show that metformin can also prevent tumors and even treat tumors.

Lung cancer is a disease that seriously jeopardizes human health. It has a high incidence rate, a high mortality rate, and a very poor prognosis. 86% of patients died within 5 years after diagnosis. More and more studies suggest that metformin can prevent lung cancer and improve the prognosis of patients with lung cancer.

Improve intestinal flora:

Studies have shown that metformin can restore the proportion of the intestinal flora and shift it towards health. Provides an advantageous living environment for the beneficial bacteria of the intestine, thereby reducing blood glucose and positively regulating the immune system.

Expected to treat some autism:

Recently, researchers at McGill University have found that metformin treats some forms of autism in fragile X syndrome, and the innovative study was published in the Nature Nature magazine. Currently, autism is one of many medical conditions that scientists believe can be treated with metformin.

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