We all have this kind of experience: When we are seriously ill, we do not want to eat anything, and the appetite subsides. How can the body fight disease without energy? Is this not to give the germs their energy and starve them with poisonous drugs?
This very natural idea… is actually wrong. When you are sick, you don’t have appetite for not killing germs, but for them to “break the net” and die hard.
It’s true that all the creatures in this world need iron to survive. Iron can transport oxygen, help metabolism, and eliminate free radicals harmful to cells.
Although iron is not a direct source of energy for cells, cells do not eat iron directly, but it participates in various metabolic activities of cells, and iron cannot be isolated from cell growth, repair, or reproduction.
Compared with our multicellular animals, microorganisms prefer iron. Iron is an important catalyst for microbes. Without iron, their reproduction and life will slow down, and they will only be able to inefficient.
So, iron is like a “network” of microbes. Microbes all like to “surf the Internet.”
Although you and I can’t rely on the Internet to get direct energy, but the Internet does facilitate our lives, it is a catalyst for efficiency. We can buy things online, order meals, and communicate with others. The social operation has been inseparable from the Internet. It’s as if iron is involved in the many activities of cells and it makes cells live more efficiently.
If you leave the Internet, social development will stagnate, and many people will live very hard. It will be impossible for you to take delivery in this lifetime. It’s like leaving iron, microbes can’t live happily, and their “society” will collapse.
You may not know that there are more species and species of organisms in the North Atlantic than in the Pacific, which is caused by iron.
The iron-rich Sahara desert was brought to the North Atlantic by a gust of wind, giving the microbes there their favorite iron, and they could happily “surf the net” in the North Atlantic. The Pacific is far from the Sahara, so lack of iron is not conducive to microbial growth. With fewer microorganisms, the number of animals in the upper food chain is also reduced.
The Sahara desert is yellow, the North Atlantic on the left, the Indian Ocean on the right, and the Pacific is not near the Sahara desert.
If bacteria and other microorganisms are to survive, they must take iron from the environment, that is, go to the “net.” However, the mammalian body is not friendly to the microorganisms and the “mesh” is slower because the concentration of iron ions in the mammal is much lower than that required by most bacteria. For example, there are a total of 3-4 grams of iron in the human body, and because of the loss of about 2 milligrams every day due to dandruff.
Therefore, any bacteria that can breed in such an environment lacking iron in mammals can also cause infection. The bacteria are not mortal. They can take away almost all the proteins in the mammal body that contain iron and use the host’s network traffic.
Many pathogenic bacteria are equipped with a fishing rod called siderophore. They use this kind of protein fishing rod to catch iron, like crazy magnetic flux, to harvest traffic. Some pathogens are even more mad. They can also run to red blood cells to grab them.
So you guessed it, grab iron from the microbes, or give them “breaking the net” can play antibacterial effect.
The specific process is this. If the bacteria are too successful to steal the host, which is too much iron in your body, and use a lot of your body’s flow, then you will feel sick. At this time, the vertebrate’s immune system will initiate a “broken net” response (this reaction is called acute phase reaction), and the first big move is deliberately causing iron sequestration.
When the “breaking the net” reacts, the immune system will reduce the amount of iron in the blood, and it will hide more of it in the cells. It will change the wireless mindset into dial-up Internet access, leaving your body in a state of iron deficiency.
In addition to seizing iron that is already present in your body, your body will also forbid you from sending extra iron to your diet to aid in the attack. This will also prevent an extra burden on the liver.
Why does eating cause a burden on the liver when I’m sick?
Because at the time of human health, after eating, the liver synthesizes many proteins that transport nutrients. However, in the “breaking the net” activity, he felt that the liver of mammals whose iron was hollowed out by bacteria had entered the fighting state. He had no intention of synthesizing proteins that normally transport nutrients, and instead began to synthesize those that could repair cells and fight infections. Reduce “supply” protein for iron supply.
If you eat a lot of things at this time, you will only make the liver of the friendly army very busy and troublesome. It will also give the enemy bacteria their favorite iron and other rare materials. You are not immune to the immune system, so to protect your body, your appetite is severed when it is severely infected.
So you get it. Having no appetite when you are sick is actually a defensive reaction of the immune system to protect you. The main purpose is to cut off the iron supply of germs, and let them grow up in the Internet 3.0 environment because of the “breaking of the net”. Life can not take care of themselves.
This also tells us that when you are sick and don’t have appetite, do not forcibly eat nutrients, especially iron-containing ones, which may have the opposite effect.
Let’s take a look at some of the tragic cases caused by “nutrition”.
Those who have a lot of iron in their bodies, such as those who suffer from hemochromatosis, are particularly favored by bacteria. Because the iron signals in their bodies are full, they are more likely to fall ill due to a large number of germs.
In addition, remember the super infectious disease in the Middle Ages – the Black Death?
The disease is caused mainly by a species of bacteria called the plague bacillus. As microorganisms, they need a lot of iron.
In medieval Europe, many civilians were afflicted with iron deficiency due to malnutrition, especially the elderly, children and women. However, young men are not the same. They have more iron in their bodies and “faster” speed, so they are more likely to be attacked by the Black Death. This is one of the reasons why young men who die from the Black Death are mostly young adults.
Therefore, long-term anemia is a kind of life-contingency strategy that hurts the enemy: you don’t come over, and when you come back I just pull out my network cable!