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I. Drugs that cause gastrointestinal mucosal damage

Patients should avoid lying down for at least 30 minutes after taking the following drugs.

1, minocycline

Tetracycline antibiotics. Chewing can cause esophageal ulcers. When the product is left in the esophagus and disintegrates, it will cause esophageal ulcers, so it should be more water, especially when taken before going to bed.

2, erythromycin

Macrolide antibiotics. Gastrointestinal reactions include diarrhea, nausea, vomiting, abdominal pain, tongue pain, and loss of appetite. Enteric-coated tablets were made into whole tablets.

3, benproperine

Dual antitussives, both central and peripheral dual mechanisms for irritating dry cough. If you take it after chewing, it can cause oral numbness.

4, potassium chloride

For the prevention and treatment of hypokalemia. On the gastrointestinal tract have a strong irritant, such as chew after taking gastrointestinal ulcers can occur, necrosis or stenosis embolism.

5, alendronate sodium phosphate

It is used to treat osteoporosis in postmenopausal women. All bisphosphonates have local irritation to the upper gastrointestinal mucosa. Chewing can cause oral ulcers, esophagitis, esophageal ulcers and esophageal erosion, and even esophageal stenosis or perforation.

Use only on a fixed weekly morning. Serve with a full glass of white water, and the patient should avoid lying down at least 30 minutes after taking the drug and before the first meal on the day.

6, aspirin, compound acetylsalicylic acid (APC), indomethacin

Non-steroidal antipyretic analgesics. Crush after stimulating the digestive tract to cause nausea, vomiting, upper abdominal discomfort or pain. (Aspirin must be used to chew the first aid for myocardial infarction)

7, propafenone

Anti-arrhythmic drugs. With local anesthetic effect, chewing can cause dry mouth and numbness of lips and tongue. In addition, the drug may affect the patient’s response, impairing the patient’s ability to drive or operate the machine. After drinking more prominent.

8, Sodium valproate

Anti-epileptic drugs, due to stimulation of oral and gastric mucosa should not be chew.

II. Drugs that are vulnerable to destruction by gastric fluid

9. Bromelain

Used for anti-inflammatory, anti-edematous proteolytic enzymes. After chewing, it is easily destroyed by pepsin in the stomach.

10, multi-enzyme tablets, trypsin tablets, compound pancreatic enzyme tablets

For loss of appetite, indigestion. This type of drug is a digestive enzyme preparation. If it is digested on the one hand, it can cause severe oral ulcers by digesting the oral mucosa. On the other hand, the drug itself can be decomposed by stomach acid and lose its efficacy.

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