Sage Therapeutics announced on May 30 that the FDA has accepted a new drug marketing application (NDA) for brexanolone (SAGE-547) intravenous injection to treat postpartum depression and granted priority review status. The PDUFA is scheduled to expire on December 19, 2018. Brexanolone is an allosteric modulator of the gamma-aminobutyric acid… Continue Reading The First Postpartum Depression New Drug Applicant Listed, Obtained FDA Priority Review Qualification
Gilead announced on May 30 that China’s State Drug Administration approved Epclusa (sophobavir 400 mg/Vepatavir 100 mg, Chinese brand name BingTongSha) for the treatment of the gene type 1-6 chronic hepatitis C virus (HCV). Adult infected patients. The State Drug Administration also approved that Epclusa combined with ribavirin (RBV) can… Continue Reading Gilead Genes 1~6 Hepatitis C New Drug Epclusa Approved for Listing in China
Alzheimer’s disease may have originated from some unknown type of diabetes! This rather shocking hypothesis is expected to open up new avenues for the treatment of Alzheimer’s disease and even to find preventive measures. “Alzheimer’s disease is diabetes in the brain.” This remark first aroused great repercussions in the field… Continue Reading Is Alzheimer’s disease called “Type III” diabetes?
Inhaled corticosteroids (ICSs) are important anti-asthmatic drugs that can act directly on the local respiratory and lung tissues. It is a first-line treatment for patients with asthma and COPD because of its rapid onset of action and low systemic adverse reactions. Local adverse reactions are common adverse reactions after long-term… Continue Reading Prevention and Treatment of Local Adverse Effects of Inhaled Glucocorticoids
Hemophilia is a hereditary blood coagulation dysfunction hemorrhagic disease with the disease gene located on the X chromosome, excluding about a third of spontaneous mutations or genetic changes. Men are mainly affected, and women are mostly “carriers.” Common features of hemophilia are active thrombinogenic disorders, prolonged clotting time, and a… Continue Reading Progress in Clinical Drugs for Hemophilia
Special warning 1. Ribavirin enters red blood cells, has a large accumulation and slows down, and has a plasma half-life of approximately 300 hours after discontinuation. The main clinical toxicity of ribavirin is hemolytic anemia. Before treatment, hematology and blood biochemistry should be performed on the 2nd week, 4th week… Continue Reading Ribavilin, the suitable is the right one
In a large LEADER study involving 9340 patients with type 2 diabetes with higher cardiovascular risk, liraglutide reduced the risk of cardiovascular death, non-fatal MI, and non-fatal stroke by 13%. The risk of death was reduced by 15% and the risk of cardiovascular death was reduced by 22%. At the… Continue Reading Liraglutide: Got natural hypoglycemic, part-time weight loss, but dislike for no effect on heart failure?
In radiography, radiography is used to take up a substance with a high atomic number and then to take a radiograph in the body to be diagnosed for medical diagnosis. With the continuous development of medical science and technology, iodinated contrast agents are widely used in clinical areas: such as… Continue Reading Reasonable application of iodine contrast agent
In 1999, the WHO announced that obesity was a chronic metabolic disease caused by multiple factors. Obesity is characterized by an increase in the volume and number of fat cells in the body, an abnormal increase in the percentage of body fat, and excessive fat deposition in the body. Obesity… Continue Reading How to choose among the overwhelming weight loss advertisements?
Ms. Zhang suffers from respiratory infections. Her prescription is a box of levofloxacin tablets. After 3 days, her condition improved, but she had erythema and itching on the upper arm skin. So She went back to hospital again. The dermatologist diagnosed the drug caused a photoallergic rash. The new prescription… Continue Reading Summer is coming: Who takes these medicines should avoid the sun!